VITA aligns H&E slides and RNA signatures in a shared latent space, then imputes a patient's RNA signature by retrieving morphologically similar historical cases, reaching 0.72 classification accuracy and 0.66 Spearman correlation.
and Chen, Bowen and Zhang, Andrew and Williamson, Drew F
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Zero-Cost Virtual RNA: Approximating Immunotherapy Signatures via Cross-Modal WSI Retrieval
VITA aligns H&E slides and RNA signatures in a shared latent space, then imputes a patient's RNA signature by retrieving morphologically similar historical cases, reaching 0.72 classification accuracy and 0.66 Spearman correlation.