Covariate adjustment for the win odds becomes feasible by connecting it to the marginal probabilistic index, yielding more precise estimators and increased power in CVOTs when covariates are prognostic.
Dapagliflozin and cardiovascular outcomes in type 2 diabetes.New England Journal of Medicine, 380(4):347– 357, 2019
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Covariate Adjustment for the Win Odds: Application to Cardiovascular Outcomes Trials
Covariate adjustment for the win odds becomes feasible by connecting it to the marginal probabilistic index, yielding more precise estimators and increased power in CVOTs when covariates are prognostic.