A GEE-based stacked M-estimation framework merges propensity score and marginal structural models to directly compute the large-sample variance of the IPTW estimator from pilot data for prospective sample size planning, with bootstrap stabilization.
Page 20 of 26 James W Antoon, Jyotirmoy Sarker, Abdullah Abdelaziz, Pei-Wen Lien, Derek J Williams, Todd A Lee, and Carlos G Grijalva
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Estimator-Aligned Prospective Sample Size Determination for Designs Using Inverse Probability of Treatment Weighting
A GEE-based stacked M-estimation framework merges propensity score and marginal structural models to directly compute the large-sample variance of the IPTW estimator from pilot data for prospective sample size planning, with bootstrap stabilization.