Simulation-based inference reconstructs biomolecular folding landscapes and dynamics from single two-second trajectories, matching established methods that require 10-100 times more data.
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy.Nature Methods, 5(6):491–505
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Quantitative and Predictive Folding Models from Limited Single-Molecule Data Using Simulation-Based Inference
Simulation-based inference reconstructs biomolecular folding landscapes and dynamics from single two-second trajectories, matching established methods that require 10-100 times more data.