Neutralization titers follow Gumbel distributions indicating influenza polyclonal responses are either collective or dominated by few strong binders, captured quantitatively by an equilibrium binding model.
(2025)Nearreal-timedataonthehuman neutralizing antibody landscape to influenza virus to in- form vaccine-strain selection in september 2025.Virus Evolution11:veaf086
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Neutralization titers reveal the structure of polyclonal antibody responses
Neutralization titers follow Gumbel distributions indicating influenza polyclonal responses are either collective or dominated by few strong binders, captured quantitatively by an equilibrium binding model.