Experiments and modeling on hyaluronic acid show kinetic superselectivity in multivalent binding, where rates are more selective than equilibrium due to a two-step model of fast weak and slow strong interactions.
On the design of precision nanomedicines.Science advances 2020,6, eaat0919
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Kinetic Superselectivity in Multivalent Binding
Experiments and modeling on hyaluronic acid show kinetic superselectivity in multivalent binding, where rates are more selective than equilibrium due to a two-step model of fast weak and slow strong interactions.