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Continuous Training and Fine-tuning for Domain-Specific Language Models in Medical Question Answering

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abstract

Large language models exhibit promising general capabilities but often lack specialized knowledge for domain-specific tasks. Developing domain experts from a base model enables a range of applications without prohibitive training costs. This work demonstrates a method using continuous training and instruction fine-tuning to rapidly adapt Llama 2 base models to the Chinese medical domain. We first conduct continuous training on 1B tokens from Chinese medical references to teach relevant vocabulary and knowledge. The models are then fine-tuned on 54K examples sourced from the Chinese National Medical Licensing Examination. Experiments on Chinese medical data confirm the effectiveness of this approach, producing a model comparable to GPT-3.5-turbo while using way less computational resource. The resulting domain-specific model could be useful for various Chinese medical applications. More broadly, this provides a template for domain-specific training of large language models in areas where pre-trained models lack the required expertise, such as law, science, and engineering.

fields

cs.CL 1

years

2025 1

verdicts

CONDITIONAL 1

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  • Continual Pre-Training is (not) What You Need in Domain Adaption cs.CL · 2025-04-18 · conditional · none · ref 12 · internal anchor

    Continued pre-training on Taiwanese legal text plus instruction tuning did not consistently improve legal reasoning over base models or LoRA routes, and DPO and ORPO alignment degraded accuracy.