A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.
Toward a foundation model of causal cell and tissue biology with a perturbation cell and tissue atlas.Cell, 187(17):4520–4545
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.CB 1years
2026 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Benchmarking virtual cell models for in-the-wild perturbation response
A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.