Kinetic theory of barrier-limited loop extrusion predicts a universal mean loop size and peaked length distributions for two-sided extrusion that match CTCF-anchored loop statistics, indicating both cohesin arms operate actively.
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SD-GLE disentangles spatial disorder from non-Markovian memory via a random field prior in variational Bayesian inference, allowing accurate extrapolation of anomalous diffusion and ensemble statistics from short trajectories in heterogeneous systems.
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Universal Loop Statistics from Active Extrusion with Kinetic Barriers
Kinetic theory of barrier-limited loop extrusion predicts a universal mean loop size and peaked length distributions for two-sided extrusion that match CTCF-anchored loop statistics, indicating both cohesin arms operate actively.
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Coarse-Grained Dynamics with Spatial Disorder and Non-Markovian Memory
SD-GLE disentangles spatial disorder from non-Markovian memory via a random field prior in variational Bayesian inference, allowing accurate extrapolation of anomalous diffusion and ensemble statistics from short trajectories in heterogeneous systems.