TriFit achieves AUROC 0.897 on ProteinGym by integrating sequence, structure, and dynamics via adaptive MoE fusion, outperforming prior supervised and zero-shot models.
TranceptEVE: Combining family-specific and family-agnostic models of protein sequences for improved fitness prediction
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TriFit: Trimodal Fusion with Protein Dynamics for Mutation Fitness Prediction
TriFit achieves AUROC 0.897 on ProteinGym by integrating sequence, structure, and dynamics via adaptive MoE fusion, outperforming prior supervised and zero-shot models.