ERBA is a new staged multimodal adapter that improves protein language model predictions of enzyme kinetic parameters by separately modeling substrate recognition and induced-fit conformational changes.
Unikp: a unified framework for the prediction of enzyme kinetic parameters.Nature communications, 14 (1):8211
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Multimodal Protein Language Models for Enzyme Kinetic Parameters: From Substrate Recognition to Conformational Adaptation
ERBA is a new staged multimodal adapter that improves protein language model predictions of enzyme kinetic parameters by separately modeling substrate recognition and induced-fit conformational changes.