One of four dual-site futile cycle networks with bifunctional enzymes exhibits simultaneous bistability and absolute concentration robustness in the final modification state, allowing two stable steady states with identical final product concentration but different intermediates.
Stochastic analysis of biochemical reaction networks with absolute concentration robustness.Journal of The Royal Society Interface, 11(93):20130943
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Bistability, Absolute Concentration Robustness, and Hysteresis in Dual-Site Futile Cycles with Bifunctional Enzymes
One of four dual-site futile cycle networks with bifunctional enzymes exhibits simultaneous bistability and absolute concentration robustness in the final modification state, allowing two stable steady states with identical final product concentration but different intermediates.