Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.
Coarse-grained model of disor- dered rna for simulations of biomolecular conden- sates.Journal of chemical theory and computa- tion, 21(5):2766–2779
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Deciphering the chemical grammar of protein-RNA condensates
Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.