Coarse-grained simulations predict that FUS-LC droplet assembly initiates at core-3 (residues 155-190), followed by core-2 and core-1, with formation times inversely correlated to stability, consistent with Ostwald's rule of stages.
Biomolecular condensates: organizers of cellular biochemistry
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Droplet growth, Ostwald's rule, and emergence of order in Fused in Sarcoma
Coarse-grained simulations predict that FUS-LC droplet assembly initiates at core-3 (residues 155-190), followed by core-2 and core-1, with formation times inversely correlated to stability, consistent with Ostwald's rule of stages.