An anisotropic reduced shell finite-element model shows that spatially graded crosslinking masks, especially smooth inverse-designed ones, produce more balanced biomechanical-optical trade-offs than uniform stiffening in a decentered keratoconus cornea.
Induction of cross-links in corneal tissue
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Sectorial customized corneal crosslinking for keratoconus: an inverse biomechanical design study with an anisotropic reduced shell finite-element surrogate
An anisotropic reduced shell finite-element model shows that spatially graded crosslinking masks, especially smooth inverse-designed ones, produce more balanced biomechanical-optical trade-offs than uniform stiffening in a decentered keratoconus cornea.