A VAE-based multiple instance learning model predicts rectal cancer lymph node metastasis from MRI with cross-validated AUC 0.858 on 168 patients, but the state-of-the-art and radiologist-exceeding claims are weakly supported.
Variational Classification
1 Pith paper cite this work. Polarity classification is still indexing.
abstract
We present a latent variable model for classification that provides a novel probabilistic interpretation of neural network softmax classifiers. We derive a variational objective to train the model, analogous to the evidence lower bound (ELBO) used to train variational auto-encoders, that generalises the softmax cross-entropy loss. Treating inputs to the softmax layer as samples of a latent variable, our abstracted perspective reveals a potential inconsistency between their anticipated distribution, required for accurate label predictions, and their empirical distribution found in practice. We augment the variational objective to mitigate such inconsistency and induce a chosen latent distribution, instead of the implicit assumption found in a standard softmax layer. Overall, we provide new theoretical insight into the inner workings of widely-used softmax classifiers. Empirical evaluation on image and text classification datasets demonstrates that our proposed approach, variational classification, maintains classification accuracy while the reshaped latent space improves other desirable properties of a classifier, such as calibration, adversarial robustness, robustness to distribution shift and sample efficiency useful in low data settings.
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cs.CV 1years
2025 1verdicts
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Interpretable Prediction of Lymph Node Metastasis in Rectal Cancer MRI Using Variational Autoencoders
A VAE-based multiple instance learning model predicts rectal cancer lymph node metastasis from MRI with cross-validated AUC 0.858 on 168 patients, but the state-of-the-art and radiologist-exceeding claims are weakly supported.