AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.
Deep geometric framework to predict antibody-antigen binding affinity.Journal of Structural Biology, page 108257, 2025
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AbICL: In-Context Learning for Antigen-Specific Antibody Affinity Ranking
AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.