Fusing trial and real-world data improves precision only for small real-world bias and small trials, and only a conservative block-jackknife interval gives honest uncertainty for that gain.
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When Does Trial-Real-World Data Fusion Improve Precision? Model Auditing and Selection-Aware Inference for Adaptive-TMLE
Fusing trial and real-world data improves precision only for small real-world bias and small trials, and only a conservative block-jackknife interval gives honest uncertainty for that gain.