PATH gene embeddings in a graph transformer achieve 0.8766 F1 on pancancer metastasis prediction (8.8% over SOTA) and identify disease-state pathway rewiring.
AR negatively regulates locally produced GH in PCa cells; GH induction following ADT enhances invasion, mesenchymal transition, and CRPC via JAK2/STAT5 and AR-V7 induction
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Graph Transformer-Based Pathway Embedding for Cancer Prognosis
PATH gene embeddings in a graph transformer achieve 0.8766 F1 on pancancer metastasis prediction (8.8% over SOTA) and identify disease-state pathway rewiring.