Intervention-aware distillation transfers mechanistic knowledge from perturbational transcriptomics to imaging phenomics for improved one-shot transfer to unseen drugs and target gene discovery.
Mapping information-rich genotype-phenotype landscapes with genome-scale perturb-seq.Cell, 185(14): 2559–2575
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Intervention-Aware Multiscale Representation Learning from Imaging Phenomics and Perturbation Transcriptomics
Intervention-aware distillation transfers mechanistic knowledge from perturbational transcriptomics to imaging phenomics for improved one-shot transfer to unseen drugs and target gene discovery.