A pair of biophysical simulations links reduced ATP free energy to shorter-lived solitons in protein alpha-helices and to hyperexcitable CA1 pyramidal neurons, proposing a thermodynamic mechanism for mental fatigue.
Illuminating dendritic function with computational models
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
citation-role summary
background 1
citation-polarity summary
fields
q-bio.NC 1years
2026 1verdicts
CONDITIONAL 1roles
background 1polarities
unclear 1representative citing papers
citing papers explorer
-
Reduced Gibbs free energy supply hinders brain information processing during mental fatigue
A pair of biophysical simulations links reduced ATP free energy to shorter-lived solitons in protein alpha-helices and to hyperexcitable CA1 pyramidal neurons, proposing a thermodynamic mechanism for mental fatigue.