Lattice simulations show that the balance of protein-lipid and protein-protein affinities plus activation switching rates determines whether membrane proteins stay dispersed, form small oligomers, or cluster inside liquid-ordered domains.
Alberts,Molecular biology of the cell(WW Norton & Com- pany, 2017)
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Coupling of Lipid Phase Behavior and Protein Oligomerization in a Lattice Model of Raft Membranes
Lattice simulations show that the balance of protein-lipid and protein-protein affinities plus activation switching rates determines whether membrane proteins stay dispersed, form small oligomers, or cluster inside liquid-ordered domains.