Masked diffusion retrofitted onto ESM2 produces a pLM that matches representation benchmarks and generates protein-like sequences, with an in-silico binder design case study.
Synonymous mutations in representative yeast genes are mostly strongly non-neutral.Nature, 606(7915): 725–731, June 2022
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Diffusion Sequence Models for Enhanced Protein Representation and Generation
Masked diffusion retrofitted onto ESM2 produces a pLM that matches representation benchmarks and generates protein-like sequences, with an in-silico binder design case study.