A new multiscale modelling framework is proposed that couples micro-scale MDE-driven ECM fibre degradation at the tumour boundary with macro-scale fibre rearrangement to study cancer invasion.
Int J Cancer 121, 1455–1462
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Extension of prior multiscale framework to heterotypic cancer invasion incorporating dynamic fiber redistribution in two-phase ECM and leading-edge MDE processes, with computational exploration of invasion patterns.
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Cell-scale degradation of peritumoural extracellular matrix fibre network and its role within tissue-scale cancer invasion
A new multiscale modelling framework is proposed that couples micro-scale MDE-driven ECM fibre degradation at the tumour boundary with macro-scale fibre rearrangement to study cancer invasion.
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Multiscale dynamics of a heterotypic cancer cell population within a fibrous extracellular matrix
Extension of prior multiscale framework to heterotypic cancer invasion incorporating dynamic fiber redistribution in two-phase ECM and leading-edge MDE processes, with computational exploration of invasion patterns.