Covariate adjustment for the win odds becomes feasible by connecting it to the marginal probabilistic index, yielding more precise estimators and increased power in CVOTs when covariates are prognostic.
Toward better practice of covariate adjust- ment in analyzing randomized clinical trials.Journal of the American Statistical Association, 118(544):2370–2382
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Covariate Adjustment for the Win Odds: Application to Cardiovascular Outcomes Trials
Covariate adjustment for the win odds becomes feasible by connecting it to the marginal probabilistic index, yielding more precise estimators and increased power in CVOTs when covariates are prognostic.