A comprehensive review supports a two-stage model in which psychedelics first increase neural sensitivity (meta-plasticity) and then drive lasting structural changes (hyper-plasticity), but it also highlights the wide gap between strong animal evidence and weak human evidence.
Mechanisms of heterosynaptic metaplasticity
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.NC 1years
2024 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Neuroplasticity and Psychedelics: a comprehensive examination of classic and non-classic compounds in pre and clinical models
A comprehensive review supports a two-stage model in which psychedelics first increase neural sensitivity (meta-plasticity) and then drive lasting structural changes (hyper-plasticity), but it also highlights the wide gap between strong animal evidence and weak human evidence.