Mitochondrial flexibility and fission-fusion balance drive axonal traffic jams and swelling in an agent-based model coupling motility, morphology, and a deformable boundary.
J.et al.Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.Human molecular genetics16,2720–2728 (2007)
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Mitochondrial mechanics nucleates axonal jamming and swelling
Mitochondrial flexibility and fission-fusion balance drive axonal traffic jams and swelling in an agent-based model coupling motility, morphology, and a deformable boundary.