Dose prioritization and inter-dose intervals in multi-dose vaccines can shift the epidemic threshold, with absolute priority to first doses at low vaccination rates and optimized scheduling at high rates under homogeneous mixing.
Cerqueira-Silva et al., The Lancet Infectious Diseases 22, 791 (2022)
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When to Boost: How Dose Timing Determines the Epidemic Threshold
Dose prioritization and inter-dose intervals in multi-dose vaccines can shift the epidemic threshold, with absolute priority to first doses at low vaccination rates and optimized scheduling at high rates under homogeneous mixing.