Sensitivity analysis using FAST and EFAST reduces a data-driven model of pembrolizumab therapy in de novo metastatic MSI-H/dMMR CRC to two simpler versions that reproduce original trajectories.
Self–class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels
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Sensitivity analysis-guided model reduction of a mathematical model of pembrolizumab therapy for de novo metastatic MSI-H/dMMR colorectal cancer
Sensitivity analysis using FAST and EFAST reduces a data-driven model of pembrolizumab therapy in de novo metastatic MSI-H/dMMR CRC to two simpler versions that reproduce original trajectories.