Two-photon photothermal microscopy reaches 0.87 uM and 0.99 uM detection limits for NADH and FAD, enabling label-free spectroscopic imaging of mitochondrial metabolic changes in cancer cells under chemotherapy.
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2026 1verdicts
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Sub-micromolar imaging of intrinsic chromophores by two-photon photothermal microscopy captures mitochondrial response to chemotherapy
Two-photon photothermal microscopy reaches 0.87 uM and 0.99 uM detection limits for NADH and FAD, enabling label-free spectroscopic imaging of mitochondrial metabolic changes in cancer cells under chemotherapy.