A phenotype-structured PDE model calibrated to melanoma data predicts three stable population behaviours and population-level hysteresis despite reversible single-cell phenotype switching.
Journal of Visualized Experiments: JoVE (138), 58149 (2018)
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A quantitative model for the emergent population dynamics of the melanoma MITF rheostat
A phenotype-structured PDE model calibrated to melanoma data predicts three stable population behaviours and population-level hysteresis despite reversible single-cell phenotype switching.