A phenotype-structured PDE model calibrated to melanoma data predicts three stable population behaviours and population-level hysteresis despite reversible single-cell phenotype switching.
Journal of the Royal Society Interface5(22), 483–505 (2008)
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.CB 1years
2026 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
A quantitative model for the emergent population dynamics of the melanoma MITF rheostat
A phenotype-structured PDE model calibrated to melanoma data predicts three stable population behaviours and population-level hysteresis despite reversible single-cell phenotype switching.