CORE-Cox learns low-rank Cox coefficients across outcomes in a source cohort then applies regularized adaptation to a target cohort, yielding C-index gains from 0.733 to 0.766 in UK Biobank and 0.628 to 0.658 in MIMIC-IV Asian subgroups under nested cross-validation.
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Structured Transfer Learning for Survival Risk Stratification in Data-Sparse Clinical Cohorts
CORE-Cox learns low-rank Cox coefficients across outcomes in a source cohort then applies regularized adaptation to a target cohort, yielding C-index gains from 0.733 to 0.766 in UK Biobank and 0.628 to 0.658 in MIMIC-IV Asian subgroups under nested cross-validation.