An information blueprint algorithm uses optimized filters on entire promoter sequences to extract condition-dependent transcription factor binding sites as collective coordinates in E. coli.
9 (A): Λνi =α ν exp −(i−c ν)2 2w2ν ,(17) with learnable centerc ν, widthw ν, and amplitudeα ν
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Informational blueprints reveal condition-dependent gene regulatory architectures
An information blueprint algorithm uses optimized filters on entire promoter sequences to extract condition-dependent transcription factor binding sites as collective coordinates in E. coli.