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Large amplitude elastic motions in proteins from a single-parameter, atomic analysis

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Learning to engineer protein flexibility

q-bio.BM · 2024-12-24 · conditional · novelty 6.0

Protein flexibility can be predicted from sequence or structure, and a fine-tuned inverse folding model can be steered toward generating sequences with increased predicted flexibility.

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  • Learning to engineer protein flexibility q-bio.BM · 2024-12-24 · conditional · none · ref 8

    Protein flexibility can be predicted from sequence or structure, and a fine-tuned inverse folding model can be steered toward generating sequences with increased predicted flexibility.