DeepFilters jointly optimizes a parameterized pupil filter and digital reconstruction network via a calibrated differentiable forward model with empirical scattering kernels to extend PSF depth from 16 to over 400 microns in clear media and recover signals beyond 120 microns in tissues.
Computational extended depth of field fluorescence microscopy in miniaturized and tabletop platforms,
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DeepFilters: Scattering-Aware Pupil Engineering with Learned Digital Filter Reconstruction for Extended Depth of Field Microscopy
DeepFilters jointly optimizes a parameterized pupil filter and digital reconstruction network via a calibrated differentiable forward model with empirical scattering kernels to extend PSF depth from 16 to over 400 microns in clear media and recover signals beyond 120 microns in tissues.