RIDER improves RNA 3D structural similarity by over 100% using RL-guided diffusion and discovers non-native sequence designs.
Integrating end-to-end learning with deep geometrical potentials for ab initio rna structure pre- diction.Nature Communications, 14(1):5745, 2023
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RIDER: 3D RNA Inverse Design with Reinforcement Learning-Guided Diffusion
RIDER improves RNA 3D structural similarity by over 100% using RL-guided diffusion and discovers non-native sequence designs.