ConforNets use channel-wise affine transforms on pre-Pairformer pair latents in OpenFold3 to achieve state-of-the-art unsupervised generation of alternate protein states and supervised conformational transfer across families.
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2 Pith papers cite this work. Polarity classification is still indexing.
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2026 2representative citing papers
EmbedOpt optimizes the conditional embedding of protein diffusion models at inference time to shift the structural prior toward experimental constraints, outperforming coordinate-based posterior sampling on cryo-EM fitting while remaining robust across hyperparameter ranges.
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ConforNets: Latents-Based Conformational Control in OpenFold3
ConforNets use channel-wise affine transforms on pre-Pairformer pair latents in OpenFold3 to achieve state-of-the-art unsupervised generation of alternate protein states and supervised conformational transfer across families.
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Robust Inference-Time Steering of Protein Diffusion Models via Embedding Optimization
EmbedOpt optimizes the conditional embedding of protein diffusion models at inference time to shift the structural prior toward experimental constraints, outperforming coordinate-based posterior sampling on cryo-EM fitting while remaining robust across hyperparameter ranges.