A controlled benchmark shows protein primary sequence representations achieve only moderate discriminative performance (best F1 0.704) for Parkinson's disease classification, with substantial class overlap and no significant differences across methods.
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Limitations of Sequence-Based Protein Representations for Parkinson's Disease Classification: A Leakage-Free Benchmark
A controlled benchmark shows protein primary sequence representations achieve only moderate discriminative performance (best F1 0.704) for Parkinson's disease classification, with substantial class overlap and no significant differences across methods.