B²-FIC calibrates Bayesian phase-II borrowing for type I error, then uses IA1 predictive probability to schedule the earliest admissible IA2, yielding earlier decisions than fixed GSD when evidence is favorable while holding empirical FWER near 0.025.
Bayesian Prediction of Event Times Using Mixture Model for Blinded Randomized Controlled Trials.Statistics in Medicine
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
stat.AP 1years
2026 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
A Bayesian predictive framework for adaptive interim-analysis timing with robust borrowing in confirmatory trials
B²-FIC calibrates Bayesian phase-II borrowing for type I error, then uses IA1 predictive probability to schedule the earliest admissible IA2, yielding earlier decisions than fixed GSD when evidence is favorable while holding empirical FWER near 0.025.