A two-parameter Ising model captures cooperativity in striated muscle thin filament activation, predicting actin-myosin interaction correlation lengths of 2-7 monomers and anti-cooperativity under Omecamtiv Mecarbil.
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Ising Models of Cooperativity in Muscle Contraction
A two-parameter Ising model captures cooperativity in striated muscle thin filament activation, predicting actin-myosin interaction correlation lengths of 2-7 monomers and anti-cooperativity under Omecamtiv Mecarbil.