A review of integrative modeling approaches for intrinsically disordered proteins, covering ensemble generation, experimental back-calculation, and biological insights from PTM regulation, phase separation, and drug discovery.
J Am Chem Soc 2020, 142:15697–15710
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Biological Insights from Integrative Modeling of Intrinsically Disordered Protein Systems
A review of integrative modeling approaches for intrinsically disordered proteins, covering ensemble generation, experimental back-calculation, and biological insights from PTM regulation, phase separation, and drug discovery.