Component-removing blind source separation can collapse causal graph recovery to zero in synthetic calcium traces and dramatically densify connectivity estimates from real v2a-RSN traces, so BSS denoising is not a neutral preprocessing step.
Granger causality analysis of fMRI BOLD signals is invariant to hemodynamic convolution but not downsampling.NeuroImage2013,65, 540–555
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Blind Source Separation Can Distort Behavior and Connectivity Analyses of Calcium Transients
Component-removing blind source separation can collapse causal graph recovery to zero in synthetic calcium traces and dramatically densify connectivity estimates from real v2a-RSN traces, so BSS denoising is not a neutral preprocessing step.