Advocates applying the estimand framework from clinical trials to network meta-analysis to support narrower, more specific research questions aligned with health technology assessment needs.
ICH E9 (R1) addendum on estimands and sensiti v- ity analysis in clinical trials to the guideline on statistical principl es for clinical trials
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Broad versus narrow research questions in evidence synthesis: a parallel to (and plea for) estimands
Advocates applying the estimand framework from clinical trials to network meta-analysis to support narrower, more specific research questions aligned with health technology assessment needs.