LGDiST, a latent diffusion model without external references, completes missing spatial transcriptomics values with 18% lower MSE than the prior reference-free state of the art across 26 datasets.
Deep learning and alignment of spatially resolved single-cell transcriptomes with tangram
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Latent Gene Diffusion for Spatial Transcriptomics Completion
LGDiST, a latent diffusion model without external references, completes missing spatial transcriptomics values with 18% lower MSE than the prior reference-free state of the art across 26 datasets.