A formal estimand framework defines treatment effects in platform trials on the entire concurrently eligible population and provides weighting and post-stratification estimators with asymptotic guarantees and efficiency gains over sub-study-only analyses.
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From Estimands to Robust Inference of Treatment Effects in Platform Trials
A formal estimand framework defines treatment effects in platform trials on the entire concurrently eligible population and provides weighting and post-stratification estimators with asymptotic guarantees and efficiency gains over sub-study-only analyses.