A framework is proposed to integrate estimands into meta-analyses of clinical trials to identify sources of heterogeneity from intercurrent event strategies and improve the external validity of pooled estimates for health technology assessment.
Defining and characterizing the progression of type 2 diabetes.Diabetes care2009; 32(Suppl 2): S151
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Incorporating estimands into meta-analyses of clinical trials
A framework is proposed to integrate estimands into meta-analyses of clinical trials to identify sources of heterogeneity from intercurrent event strategies and improve the external validity of pooled estimates for health technology assessment.