The MMM mediation framework delivers consistent estimators for indirect effect matrices in high-dimensional many-to-many-to-many settings, identifies genetic-neural-cognitive pathways in Alzheimer's data, and improves out-of-sample prediction.
High-dimensional Many–to–many–to–many Mediation Analysis
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High-dimensional Many-to-many-to-many Mediation Analysis
The MMM mediation framework delivers consistent estimators for indirect effect matrices in high-dimensional many-to-many-to-many settings, identifies genetic-neural-cognitive pathways in Alzheimer's data, and improves out-of-sample prediction.