A framework for robust closed-loop control of T4 production in engineered thyroid-like cells via electrically stimulated transcription-factor activation, using sampled-data adaptive PID with stability guarantees and in silico validation.
Merging machine learning and bioelectronics for closed-loop control of biological systems and homeostasis.Cell Reports Physical Science, 4(8):101535
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Sampled-data Robust Control of Electrically Stimulated Engineered Cell Factories
A framework for robust closed-loop control of T4 production in engineered thyroid-like cells via electrically stimulated transcription-factor activation, using sampled-data adaptive PID with stability guarantees and in silico validation.