GENESIS infers gene regulatory relationships by using genotype variants to anchor constraint-based causal discovery, but the paper's theoretical guarantees and empirical validation are insufficient to support the claims.
Harnessing naturally randomized transcription to infer regulatory relationships among genes
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Multi-omic Causal Discovery using Genotypes and Gene Expression
GENESIS infers gene regulatory relationships by using genotype variants to anchor constraint-based causal discovery, but the paper's theoretical guarantees and empirical validation are insufficient to support the claims.